Alternative methods for safer cosmetics
In our modern world, the trend towards individualisation and self-expression with cosmetic products is ever more important.
A producer of cosmetics is responsible for the safety of their products towards the consumer and we support you to guarantee that safety through a multitude of animal-free test methods. Our expertise ranges from the use of primary cells to permanent cell lines and 3D-tissue models and we’re happy to meet your special needs.
Our test methods
| In vitro Skin Irritation: Reconstructed Human Epidermis Test method | OECD 439 |
| EpiOral/EpiGingival Test | ISO 10993/EN ISO 7405 |
| EpiVaginal Test | ISO 10993-23 |
| In vitro Skin Corrosion: Reconstructed Human Epidermis Test method) | OECD 431 |
| In vitro Skin Corrosion: Corrositex – In vitro Membrane Barrier Test method | OECD 435 |
| Eye Irritation: Reconstructed human Cornea-like Epithelium Test method | OECD 492 |
| Bovine Cornea Opacity and Permeability Test (BCOP) | OECD 437 |
| Short Time Exposure in vitro Test Method for Identifying Eye Damage (STE) | OECD 491 |
| Hen’s Egg Test – Chorioallantoic Membrane (HET-CAM) | INVITTOX Protocol No. 47 |
| Direct Peptide Reactivity Assay (DPRA) | OECD 442C (Appendix I) |
| The ARE-Nrf2 luciferase LuSens test method (LuSens) | OECD 442D (Appendix IB) |
| Human Cell Line Activation test (h-CLAT) | OECD 442E (Annex I) |
| XTT test | ISO 10993-5 / ISO 7405 |
| MTT test | ISO 10993-5 / ISO 7405 |
| Neutral red uptake (NRU) | ISO 10993-5 / ISO 7405 |
| Agar overlay assay | ISO 10993-5 / ISO 7405 |
| Elution Test | USP 87 |
| In vitro 3T3 NRU Phototoxicity Test | OECD 432 |
| In vitro gene mutation study in bacteria: Ames Test | OECD 471 / OPPTS / ICH |
| In vitro gene mutation study in mammalian cells: Mouse Lymphoma Assay (MLTK Assay) | OECD 490 / OPPTS / ICH |
| In vitro gene mutation study in mammalian cells: HPRT test | OECD 476 / OPPTS / ICH |
| Micronucleus Assay in vitro (Human Lymphocytes or V79 cells) | OECD 487 / OPPTS / ICH |
| Chromosomal aberration Assay in vitro (Human Lymphocytes or V79 cells) | OECD 473 / OPPTS / ICH |
| Hen’s Egg Test – Induction of Micronuclei (HET-MN) |
| Cell Transformation Assay in Bhas Cells | OECD 231 (draft) |